The major part of the district is located within Transcarpathian Lowland, in the north occupying the part of the Vyhorlat-Hutynskyi mountain range and its foothills. The highest peak of Uzhhorod district is Dunavka peak which is 1018 m high and belongs to the Syniak mountain range. In this territory, there is the lowest point (101 metres above sea level) of the district within the village of Ruski Heivtsi. Tysa, Uzh and Latorytsia rivers play an important role in the relief formation. Besides, there are a lot of flumes, ponds and storage reservoirs in the lowlands.
Climate of Uzhhorod district is favourable for recreation as well as for agriculture. Summer starts in the middle of May and ends in September. Mean daily air temperatures are 15-25°С and maximum air temperatures are 36-40°С. Winter is mild, with little snow and frequent thaws. Temperatures range from -6°С to +3°С, severe frosts are very rare. According to archaeological finds, Uzhhorod district was densely populated in antiquity — camps of different periods, tracing back to the Stone Age, and medieval settlements can be found near almost every village. Found Roman coins and jewellery bear evidence of the lively trade between local people and Roman provinces Pannonia and Dacia. The most ancient Slavonic settlements, dated to the 6th century, were found in Uzhhorod and in the villages of Haloch and Holmok. In the 11-14th centuries, this district was actively being placed under cultivation by the Hungarians, the villages of Velyka Dobron, Velyki Heivtsi, Siurte and others appeared.
Lands of the district are famous for their vineyards of European sorts which local enterprises and winemakers have been using for creating wines and cognacs of high quality since olden times. Uzhhorod district is embellished with numerous exotic flora including 300 sorts of exotic plants, among them there are oriental cherry trees, magnolias, Japanese quinces, Nedzvetskyi's apple trees, catalpa trees and Himalayan pines.
In Uzhhorod district, tourists can find medieval castles and Catholic churches, monuments of garden art, resorts with mineral as well as thermal waters and tasting rooms.